Biophysics, Structural Biology, and Screening (BiSS) is a core facility of the Faculty of Medicine,聽hosted by the Department of Biomedicine.聽BiSS offers expertise and access to a range of instrumentation to study the interactions of small molecules with macromolecules, protein biophysics, and for crystallization.
BiSS is part of the chemical biology consortia and . EU-Openscreen has certified BiSS as a speciliast screening site for biophysical and virtual screening.聽BiSS hosts a number of libraries, including the 100 000-compound聽 and the 1000-compound聽,聽which can be accessed for either biophysical or fragment screens. BiSS also offers cheminformatic services for virtual screening and hit follow up. All instrumentation can be used by the users independently after appropriate training.
BiSS is a member of the national NORCRYST infrastructure funded by the Norwegian Research Council, and hosts instrumentation and know-how for macromolecular crystallography and complementary techniques. BiSS coordinates local BAG applications for synchrotron beamtime at various European large-scale research infrastructures.
