Dr. Eve Gazave, Institut Jacques Monod, France
Dr. Eve Gazave, leader of the Stem Cells, Development and Evolution group at the Institut Jacques Monod, will present: "Understanding successful regeneration in animals: Insights from the annelid Platynereis dumerilii"
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Regeneration, a fascinating biological mechanism, allows a damaged or missing part of the body to be rebuilt. In animals, regeneration is the rule rather than the exception. Indeed, most animal lineages have regenerative capabilities, although they vary greatly from one group to another. Unfortunately, mammals, and humans in particular, have extremely limited regenerative capacity. Why and how many animal species have amazing regenerative abilities, while others have extremely limited ones, is the fundamental question I am addressing with my team. For many years, we have been developing a powerful regeneration model, the annelid Platynereis dumerilii. This model species is uniquely suited to address this question, as it displays two types of successful regeneration, its tail and limbs, as well as an abortive one, its head. We are therefore implementing a comparative approach within the different regenerative contexts of Platynereis to identify the convergent and divergent molecular and cellular processes that lead to these different outcomes.
